Po-Ru Loh: search on Z-Library

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1

Genetic Evidence for Recent Population Mixture in India

Moorjani, Priya, Thangaraj, Kumarasamy, Patterson, Nick, Lipson, Mark, Loh, Po-Ru, Govindaraj, Periyasamy, Berger, Bonnie, Reich, David, Singh, Lalji

Journal:

The American Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 884 KB

english, 2013

2

Stepping to Infinity Along Gaussian Primes

Journal:

American Mathematical Monthly

Year:

2007

Language:

english

File:

PDF, 1010 KB

english, 2007

3

Fast, sensitive and accurate integration of single-cell data with Harmony

Korsunsky, Ilya, Millard, Nghia, Fan, Jean, Slowikowski, Kamil, Zhang, Fan, Wei, Kevin, Baglaenko, Yuriy, Brenner, Michael, Loh, Po-ru, Raychaudhuri, Soumya

Journal:

Year:

2019

File:

PDF, 5.09 MB

2019

4

Stepping to Infinity Along Gaussian Primes

Journal:

American Mathematical Monthly

Year:

2007

Language:

english

File:

PDF, 382 KB

english, 2007

5

p-ADIC AND COMBINATORIAL PROPERTIES OF MODULAR FORM COEFFICIENTS

LOH, PO-RU, RHOADES, ROBERT C.

Journal:

International Journal of Number Theory

Year:

2006

Language:

english

File:

PDF, 296 KB

english, 2006

6

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Bulik-Sullivan, Brendan K, Loh, Po-Ru, Finucane, Hilary K, Ripke, Stephan, Yang, Jian, Patterson, Nick, Daly, Mark J, Price, Alkes L, Neale, Benjamin M

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 593 KB

english, 2015

7

An atlas of genetic correlations across human diseases and traits

Bulik-Sullivan, Brendan, Finucane, Hilary K, Anttila, Verneri, Gusev, Alexander, Day, Felix R, Loh, Po-Ru, Duncan, Laramie, Perry, John R B, Patterson, Nick, Robinson, Elise B, Daly, Mark J, Price, Al

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 670 KB

english, 2015

8

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

Reshef, Yakir A., Finucane, Hilary K., Kelley, David R., Gusev, Alexander, Kotliar, Dylan, Ulirsch, Jacob C., Hormozdiari, Farhad, Nasser, Joseph, O’Connor, Luke, van de Geijn, Bryce, Loh, Po-Ru, Gros

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 7.44 MB

english, 2018

9

Prize-based contests can provide solutions to computational biology problems

Lakhani, Karim R, Boudreau, Kevin J, Loh, Po-Ru, Backstrom, Lars, Baldwin, Carliss, Lonstein, Eric, Lydon, Mike, MacCormack, Alan, Arnaout, Ramy A, Guinan, Eva C

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 515 KB

english, 2013

10

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, Bjarni J., Yang, Jian, Finucane, Hilary K., Gusev, Alexander, Lindström, Sara, Ripke, Stephan, Genovese, Giulio, Loh, Po-Ru, Bhatia, Gaurav, Do, Ron, Hayeck, Tristan, Won, Hong-Hee, Kath

Journal:

The American Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 492 KB

english, 2015

11

Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes

Chung, Wonil, Chen, Jun, Turman, Constance, Lindstrom, Sara, Zhu, Zhaozhong, Loh, Po-Ru, Kraft, Peter, Liang, Liming

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.25 MB

english, 2019

12

Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits

Hormozdiari, Farhad, Gazal, Steven, van de Geijn, Bryce, Finucane, Hilary K., Ju, Chelsea J.-T., Loh, Po-Ru, Schoech, Armin, Reshef, Yakir, Liu, Xuanyao, O’Connor, Luke, Gusev, Alexander, Eskin, Eleaz

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 3.06 MB

english, 2018

13

Assessing statistical significance in causal graphs

Leonid Chindelevitch, Po-Ru Loh, Ahmed Enayetallah, Bonnie Berger, Daniel Ziemek

Journal:

BMC Bioinformatics

Year:

2012

Language:

english

File:

PDF, 402 KB

english, 2012

14

Physical and neurobehavioral determinants of reproductive onset and success

Day, Felix R, Helgason, Hannes, Chasman, Daniel I, Rose, Lynda M, Loh, Po-Ru, Scott, Robert A, Helgason, Agnar, Kong, Augustine, Masson, Gisli, Magnusson, Olafur Th, Gudbjartsson, Daniel, Thorsteinsdo

Journal:

Nature Genetics

Year:

2016

Language:

english

File:

PDF, 1.00 MB

english, 2016

15

Reference-based phasing using the Haplotype Reference Consortium panel

Loh, Po-Ru, Danecek, Petr, Palamara, Pier Francesco, Fuchsberger, Christian, A Reshef, Yakir, K Finucane, Hilary, Schoenherr, Sebastian, Forer, Lukas, McCarthy, Shane, Abecasis, Goncalo R, Durbin, Ric

Journal:

Nature Genetics

Year:

2016

Language:

english

File:

PDF, 556 KB

english, 2016

16

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection

Schoech, Armin P., Jordan, Daniel M., Loh, Po-Ru, Gazal, Steven, O’Connor, Luke J., Balick, Daniel J., Palamara, Pier F., Finucane, Hilary K., Sunyaev, Shamil R., Price, Alkes L.

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 807 KB

english, 2019

17

Two-Variance-Component Model Improves Genetic Prediction in Family Datasets

Tucker, George, Loh, Po-Ru, MacLeod, Iona M., Hayes, Ben J., Goddard, Michael E., Berger, Bonnie, Price, Alkes L.

Journal:

The American Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 327 KB

english, 2015

18

Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia

Galinsky, Kevin J., Bhatia, Gaurav, Loh, Po-Ru, Georgiev, Stoyan, Mukherjee, Sayan, Patterson, Nick J., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 1.97 MB

english, 2016

19

Author Correction: Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

Gazal, Steven, Finucane, Hilary K., Furlotte, Nicholas A., Loh, Po-Ru, Palamara, Pier Francesco, Liu, Xuanyao, Schoech, Armin, Bulik-Sullivan, Brendan, Neale, Benjamin M., Gusev, Alexander, Price, Alk

Journal:

Nature Genetics

Year:

2019

File:

PDF, 477 KB

2019

20

Estimating cross-population genetic correlations of causal effect sizes

Galinsky, Kevin J., Reshef, Yakir A., Finucane, Hilary K., Loh, Po-Ru, Zaitlen, Noah, Patterson, Nick J., Brown, Brielin C., Price, Alkes L.

Journal:

Genetic Epidemiology

Year:

2018

Language:

english

File:

PDF, 488 KB

english, 2018

21

Efficient Bayesian mixed-model analysis increases association power in large cohorts

Loh, Po-Ru, Tucker, George, Bulik-Sullivan, Brendan K, Vilhjálmsson, Bjarni J, Finucane, Hilary K, Salem, Rany M, Chasman, Daniel I, Ridker, Paul M, Neale, Benjamin M, Berger, Bonnie, Patterson, Nick,

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 774 KB

english, 2015

22

A Robust Example of Collider Bias in a Genetic Association Study

Day, Felix R., Loh, Po-Ru, Scott, Robert A., Ong, Ken K., Perry, John R.B.

Journal:

The American Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 376 KB

english, 2016

23

Mixed-model association for biobank-scale datasets

Loh, Po-Ru, Kichaev, Gleb, Gazal, Steven, Schoech, Armin P., Price, Alkes L.

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

24

Reconstructing Austronesian population history in Island Southeast Asia

Lipson, Mark, Loh, Po-Ru, Patterson, Nick, Moorjani, Priya, Ko, Ying-Chin, Stoneking, Mark, Berger, Bonnie, Reich, David

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 453 KB

english, 2014

25

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Loh, Po-Ru, Bhatia, Gaurav, Gusev, Alexander, Finucane, Hilary K, Bulik-Sullivan, Brendan K, Pollack, Samuela J, de Candia, Teresa R, Lee, Sang Hong, Wray, Naomi R, Kendler, Kenneth S, O'Donovan, Mich

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 1018 KB

english, 2015

26

Mixed Model Association with Family-Biased Case-Control Ascertainment

Hayeck, Tristan J., Loh, Po-Ru, Pollack, Samuela, Gusev, Alexander, Patterson, Nick, Zaitlen, Noah A., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Year:

2017

Language:

english

File:

PDF, 175 KB

english, 2017

27

Chromosomal alterations among age-related haematopoietic clones in Japan

Terao, Chikashi, Suzuki, Akari, Momozawa, Yukihide, Akiyama, Masato, Ishigaki, Kazuyoshi, Yamamoto, Kazuhiko, Matsuda, Koichi, Murakami, Yoshinori, McCarroll, Steven A., Kubo, Michiaki, Loh, Po-Ru, Ka

Journal:

Year:

2020

File:

PDF, 7.25 MB

2020

28

Monogenic and polygenic inheritance become instruments for clonal selection

Loh, Po-Ru, Genovese, Giulio, McCarroll, Steven A.

Journal:

Year:

2020

File:

PDF, 21.34 MB

2020

29

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

Hayeck, Tristan J., Zaitlen, Noah A., Loh, Po-Ru, Vilhjalmsson, Bjarni, Pollack, Samuela, Gusev, Alexander, Yang, Jian, Chen, Guo-Bo, Goddard, Michael E., Visscher, Peter M., Patterson, Nick, Price, A

Journal:

The American Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 204 KB

english, 2015

30

Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure

Galinsky, Kevin J., Loh, Po-Ru, Mallick, Swapan, Patterson, Nick J., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 1.33 MB

english, 2016

31

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases

Zhu, Zhaozhong, Lee, Phil H., Chaffin, Mark D., Chung, Wonil, Loh, Po-Ru, Lu, Quan, Christiani, David C., Liang, Liming

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 1.81 MB

english, 2018

32

GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation

Terao, Chikashi, Momozawa, Yukihide, Ishigaki, Kazuyoshi, Kawakami, Eiryo, Akiyama, Masato, Loh, Po-Ru, Genovese, Giulio, Sugishita, Hiroki, Ohta, Tazro, Hirata, Makoto, Perry, John R. B., Matsuda, Ko

Journal:

Nature Communications

Year:

2019

File:

PDF, 1024 KB

2019

33

Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations

Gazal, Steven, Loh, Po-Ru, Finucane, Hilary K., Ganna, Andrea, Schoech, Armin, Sunyaev, Shamil, Price, Alkes L.

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 2.83 MB

english, 2018

34

Phenotype Prediction Using Regularized Regression on Genetic Data in the DREAM5 Systems Genetics B Challenge

Loh, Po-Ru, Tucker, George, Berger, Bonnie, Isalan, Mark

Journal:

Year:

2011

Language:

english

File:

PDF, 1.27 MB

english, 2011

35

Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations

Loh, Po-Ru, Genovese, Giulio, Handsaker, Robert E., Finucane, Hilary K., Reshef, Yakir A., Palamara, Pier Francesco, Birmann, Brenda M., Talkowski, Michael E., Bakhoum, Samuel F., McCarroll, Steven A.

Journal:

Year:

2018

Language:

english

File:

PDF, 4.60 MB

english, 2018

36

Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes

Chung, Wonil, Chen, Jun, Turman, Constance, Lindstrom, Sara, Zhu, Zhaozhong, Loh, Po-Ru, Kraft, Peter, Liang, Liming

Journal:

Nature Communications

Year:

2019

File:

PDF, 1.25 MB

2019

37

Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach

Meyer, Pablo, Cokelaer, Thomas, Chandran, Deepak, Kim, Kyung, Loh, Po-Ru, Tucker, George, Lipson, Mark, Berger, Bonnie, Kreutz, Clemens, Raue, Andreas, Steiert, Bernhard, Timmer, Jens, Bilal, Erhan, D

Journal:

BMC Systems Biology

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

38

Stepwise Distributed Open Innovation Contests for Software Development - Acceleration of Genome-Wide Association Analysis

Hill, Andrew, Loh, Po-Ru, Bharadwaj, Ragu B., Pons, Pascal, Shang, Jingbo, Guinan, Eva, Lakhani, Karim, Kilty, Iain, Jelinsky, Scott A.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

39

Fast and accurate long-range phasing in a UK Biobank cohort

Loh, Po-Ru, Palamara, Pier Francesco, Price, Alkes L

Journal:

Nature Genetics

Year:

2016

Language:

english

File:

PDF, 532 KB

english, 2016

40

Multiethnic polygenic risk scores improve risk prediction in diverse populations

Márquez-Luna, Carla, Loh, Po-Ru, Price, Alkes L.

Journal:

Genetic Epidemiology

Year:

2017

Language:

english

File:

PDF, 513 KB

english, 2017

41

Leveraging Polygenic Functional Enrichment to Improve GWAS Power

Kichaev, Gleb, Bhatia, Gaurav, Loh, Po-Ru, Gazal, Steven, Burch, Kathryn, Freund, Malika K., Schoech, Armin, Pasaniuc, Bogdan, Price, Alkes L.

Journal:

The American Journal of Human Genetics

Year:

2018

Language:

english

File:

PDF, 609 KB

english, 2018

42

Compressive genomics

Loh, Po-Ru, Baym, Michael, Berger, Bonnie

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 327 KB

english, 2012

43

Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

Gazal, Steven, Finucane, Hilary K, Furlotte, Nicholas A, Loh, Po-Ru, Palamara, Pier Francesco, Liu, Xuanyao, Schoech, Armin, Bulik-Sullivan, Brendan, Neale, Benjamin M, Gusev, Alexander, Price, Alkes

Journal:

Nature Genetics

Year:

2017

Language:

english

File:

PDF, 741 KB

english, 2017

44

Heritability of Atrial FibrillationCLINICAL PERSPECTIVE

Weng, Lu-Chen, Choi, Seung Hoan, Klarin, Derek, Smith, J. Gustav, Loh, Po-Ru, Chaffin, Mark, Roselli, Carolina, Hulme, Olivia L., Lunetta, Kathryn L., Dupuis, Josée, Benjamin, Emelia J., Newton-Cheh,

Journal:

Circulation Cardiovascular Genetics

Year:

2017

Language:

english

File:

PDF, 843 KB

english, 2017

45

Response to Shen et al.

Galinsky, Kevin J., Bhatia, Gaurav, Loh, Po-Ru, Georgiev, Stoyan, Mukherjee, Sayan, Patterson, Nick J., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 325 KB

english, 2016

46

Author Correction: A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases

Zhu, Zhaozhong, Lee, Phil H., Chaffin, Mark D., Chung, Wonil, Loh, Po-Ru, Lu, Quan, Christiani, David C., Liang, Liming

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 481 KB

english, 2018

47

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

Lipson, Mark, Loh, Po-Ru, Sankararaman, Sriram, Patterson, Nick, Berger, Bonnie, Reich, David, Coop, Graham

Journal:

Year:

2015

Language:

english

File:

PDF, 2.43 MB

english, 2015

48

Fundamental relation between phase and group velocity, and application to the failure of perfectly matched layers in backward-wave structures

Loh, Po-Ru, Oskooi, Ardavan F., Ibanescu, Mihai, Skorobogatiy, Maksim, Johnson, Steven G.

Journal:

Physical Review E

Year:

2009

Language:

english

File:

PDF, 232 KB

english, 2009

49

Partitioning heritability by functional annotation using genome-wide association summary statistics

Finucane, Hilary K, Bulik-Sullivan, Brendan, Gusev, Alexander, Trynka, Gosia, Reshef, Yakir, Loh, Po-Ru, Anttila, Verneri, Xu, Han, Zang, Chongzhi, Farh, Kyle, Ripke, Stephan, Day, Felix R, Purcell, S

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 921 KB

english, 2015

50

A sampling framework for incorporating quantitative mass spectrometry data in protein interaction analysis

Tucker, George, Loh, Po-Ru, Berger, Bonnie

Journal:

BMC Bioinformatics

Year:

2013

Language:

english

File:

PDF, 787 KB

english, 2013

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